What are the symptoms?
Anterior uveitis most commonly shows as a single red and painful eye that is very sensitive to light. You may notice a decrease in vision or the presence of floaters as well. With proper treatment, this typically resolves and leaves no lasting complications. Occasionally uveitis may become chronic or recurrent. In these cases, the eye may or may not be red and painful. If the inflammation recurs or becomes chronic there is often an underlying systemic condition that is causing the inflammation.
What causes uveitis?
Uveitis may be caused by a large number of conditions. In about half of the cases of typical uveitis, there is no cause found. If the disease becomes chronic or recurs then blood work is often needed to illicit a cause. There are a number of systemic diseases that can cause chronic or recurrent uveitis.
Iritis or uveitis occurs when there is inflammation inside the eye. This inflammation can be in the anterior, intermediate, or posterior part of the eye and can have many different causes. Most often the inflammation is seen in the anterior, or front, part of the eye. It is characterized by inflammation of the iris. Intermediate and posterior uveitis occurs in the deeper parts of the eye and can affect the vitreous, retina, and choroid.
Systemic disorders that can cause uveitis to include:
⁃ Behçet’s disease
⁃ Birdshot retinochoroidopathy
⁃ Brucellosis
⁃ Herpes simplex
⁃ Herpes zoster
⁃ Inflammatory bowel disease
⁃ Juvenile rheumatoid arthritis
⁃ Kawasaki’s disease
⁃ Presumed ocular histoplasmosis syndrome
⁃ Multiple sclerosis
⁃ Psoriatic arthritis
⁃ Reiter’s syndrome
⁃ Sarcoidosis
⁃ Syphilis
⁃ Systemic lupus erythematosus
⁃ Toxocariasis
⁃ Toxoplasmosis
⁃ Tuberculosis
⁃ Vogt-Koyanagi-Harada syndrome
There are also a number of ocular disorders that can present with inflammation inside the eye. These are not primarily inflammatory but can cause an eye problem that looks like uveitis. Ocular disorders that can mimic uveitis include:
⁃ Juvenile xanthogranuloma
⁃ Leukemia
⁃ Malignant melanoma
⁃ Retinal detachment
⁃ Lymphoma
⁃ Reticulum cell sarcoma
⁃ Retinitis pigmentosa